Background

Mantle cell lymphoma (MCL) is a malignant B-cell neoplasm considered an aggressive non-Hodgkin lympoma with a propensity for extranodal involvement. 

Case History

Presentation as per the case below identified extranodal involvement of the submandibular, sublingual, and minor salivary gland involvement but sparing the parotid glands.

References

Abukhiran I, Jasser J, Hoffman HT, Syrbu S. Mantle Cell Lymphoma Involving Major and Minor Salivary Glands With Parotid Sparing. JAMA Otolaryngol Head Neck Surg. 2020 Mar 1;146(3):309-311. doi: 10.1001/jamaoto.2019.4116. PMID: 31895458.

Rajkumar K, Rao R, Chawla N, Bandyopadhyay TK, Sinha R:.Mantle cell lymphoma of the oral cavity with multiple foci: a case report and review of the literature.J Maxillofac Oral Surg. 2015 Mar;14(Suppl 1):138-44. doi: 10.1007/s12663-012-0383-5. Epub 2012 May 16.

Sander B, Quintanilla-Martinez L, Ott G, Xerri L, Kuzu I, Chan JK, Swerdlow SH, Campo E.Mantle cell lymphoma--a spectrum from indolent to aggressive disease.Virchows Arch. 2016 Mar;468(3):245-57. doi: 10.1007/s00428-015-1840-6. Epub 2015 Aug 23.

Marcucci M, Marcucci G, Cordeiro MS, León JE, Araujo JP, de Oliveira JX, Santos KCP:Mantle cell lymphoma: involvement of nodal and extranodal sites in the head and neck, with multifocal oral lesions.Autops Case Rep. 2017 Sep 30;7(3):26-31. doi: 10.4322/acr.2017.030. eCollection 2017 Jul-Sep.