Friday, May 12, 2017

Updated by Piper Wenzel, BS April 2024

See also:

General Considerations

  • Pediatric patients have weight-based minimum fluid intake requirements. In patients who have had tonsillectomies or other procedures affecting their ability to swallow, their daily fluid requirements should be calculated prior to discharge to determine if they will be able to stay adequately hydrated with PO intake once they are no longer receiving IV fluids.
  • The Holliday-Segar Method provides a formula for calculating fluid requirements (Holliday-Segar 1957) - contemporary articles support continued use of this method with modifications based on overall health of the child with individualized rates of IV fluids "accounting for enteral fluid intake, IV medication fluids, and fluid loss (Alexander 2022) .
  • Clinicians should be aware of clinical signs of dehydration and respond appropriately.

Signs of Dehydration

Table 1: Adapted from (Santillanes 2018, Alexander 2022, Cellucci 2023) 

DehydrationMildModerateSevere 
Fluid lossChild: 3% (30 cc/kg)Child: 6% (60 cc/kg)Child: 9% (90 cc/kg) 
 Infant: 5% (50 cc/kg)Infant: 10% (100 cc/kg)Infant: 15% (150 cc/kg) 
Skin turgorNormalTentingNone 
Skin moistureNormalDryClammy 
LipsMoistDryParched 
EyesNormalDeep setSunken 
TearsPresentReducedAbsent 
FontanelleFlatSoftSunken 
MoodConsolableIrritableObtunded 
PulseRegularMildly increasedTachycardic 
Urine OutputNormalDecreasedAnuric 

Holliday-Segar Method

  1. Daily fluid requirements (Holliday and Segar 1957)
    • 100 cc/kg for 1st 10 kg of the patient's weight
    • 50 cc/kg for the 2nd 10 kg of the patient's weight
    • 20 cc/kg for the remaining weight
  2. Fluid requirements per hour: Daily fluid requirements are divided into approximate hourly rates which gives the "4-2-1" formula often used to calculate hourly infusion rates of IV fluids (Zieg 2024).
    • 100 cc/kg/24 hours= 4 cc/kg/hour for the 1st 10 kg of the patient's weight
    • 50 cc/kg/24 hours= 2 cc/kg/hour for the 2nd 10 kg of the patient's weight
    • 20 cc/kg/24 hours= 1 cc/kg/hour for the remaining weight
  3. Example: A 35 kg child minimum hourly fluid intake would be: (4x10) + (2x10) + (1x15) = 75 cc/hour

Table 2: Quick reference for minimum fluid requirements (based on 4-2-1 formula above from Zieg 2024)

WeightMinimum fluid intake
per hour
Minimum fluid intake
per 8 hour shift
1 kg4 cc/hour32 cc/shift
2 kg8 cc/hour64 cc/shift
3 kg12 cc/hour96 cc/shift
4 kg16 cc/hour128 cc/shift
5 kg20 cc/hour160 cc/shift
6 kg24 cc/hour192 cc/shift
7 kg28 cc/hour224 cc/shift
8 kg32 cc/hour256 cc/shift
9 kg36 cc/hour288 cc/shift
10 kg40 cc/hour320 cc/shift
11 kg42 cc/hour336 cc/shift
12 kg44 cc/hour352 cc/shift
13 kg46 cc/hour368 cc/shift
14 kg48 cc/hour384 cc/shift
15 kg50 cc/hour400 cc/shift
16 kg52 cc/hour416 cc/shift
17 kg54 cc/hour432 cc/shift
18 kg56 cc/hour448 cc/shift
19 kg58 cc/hour464 cc/shift
20 kg60 cc/hour480 cc/shift
25 kg65 cc/hour520 cc/shift
30 kg70 cc/hour560 cc/shift

References

Flint et al. General Considerations in Pediatric Otolaryngology. Fluids and fluid management. Cummings Otolaryngology: Head and Neck Surgery, 5th ed. Chapter 180.

Holliday MA, Segar, WE. The maintenance need for water in parenteral fluid therapy. Journal of Pediatrics. 1957 (19) 823-832.

Alexander E, Weatherhead J, Creo A, Hanna C, Steien DB. Fluid management in hospitalized pediatric patients. Nutr Clin Pract. 2022 Oct;37(5):1033-1049. doi: 10.1002/ncp.10876. Epub 2022 Jun 24. PMID: 35748381.

Santillanes G, Rose E. Evaluation and Management of Dehydration in Children. Emerg Med Clin North Am. 2018 May;36(2):259-273. doi: 10.1016/j.emc.2017.12.004. Epub 2018 Feb 10. PMID: 29622321.

Zieg J, Narla D, Gonsorcikova L, Raina R. Fluid management in children with volume depletion. Pediatr Nephrol. 2024 Feb;39(2):423-434. doi: 10.1007/s00467-023-06080-z. Epub 2023 Jul 14. PMID: 37452205.

Cellucci MF. (2023, April). Dehydration in Children. Merck Manual Professional Version. https://www.merckmanuals.com/professional/pediatrics/dehydration-and-fluid-therapy-in-children/dehydration-in-children